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Additional resources for Decoherence through interaction with the environment
BioFactors 8, 229-234. , Nicolay, K. M. (1992). Intracellular compartmentation, structure, and function of creatine kinase isozymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis. Biochem. J. 281, 21-40. , Chung, Y. and Jue, T. (1997). Myoglobin and hemoglobin rotational diffusion in the cell. Biophys. J. 73, 2764-2770. R. and Pagliaro, L. (1997). Metabolic compartmentation in living cells: structural association of aldolase. Exp.
1996) and Ca 2+ATPase activities (Barany, 1967; Hamilton and Ianuzzo, 199 l) are higher in muscles that operate at high frequencies. Josephson (1993) proposed that such high "activation costs" may contribute to the low efficiencies of muscles that operate at high frequencies. However, this seems to be only a partial explanation, because asynchronous insect flight muscles appear to be inefficient despite their lack of a well developed SR (Ellington, 1985). , 1999). Ch. 2. Design of muscle aerobic metabolism 3.
Interspecific variations on these "themes" are described by Hochachka and Somero (1984). 1 is an abbreviated metabolic map, providing a qualitative picture of the organization of pathways of carbohydrate and fatty acid oxidation in vertebrate red and cardiac muscles. During aerobic exercise, most of the ATP is derived from mitochondrial oxidative phosphorylation. The oxidation of a mole of palmitate yields 129 moles of ATP (McGilvery and Goldstein, 1979). In muscles that utilize carbohydrate as the main oxidative fuel, glycolysis makes little direct contribution to ATP synthesis but serves an aerobic function, breaking down hexose phosphates to pyruvate in preparation for entry into the Krebs cycle.