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By Noyes W. A.

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In this chapter we aim at detailing the practical use of TMS in research and, potentially, clinical settings by discussing various procedural steps. Such a discussion can serve as a general guide for safe and proper administration of this technology. TMS MACHINES All TMS machines share a common principle, although different manufacturers have implemented specifications that facilitate certain uses.

RTMS administrators should be skilled in assessing the risk factors for the procedure and be trained in recognizing and carrying out first-line management of an epileptic seizure. Finally, the use of rTMS should comply with regulations put forward by local regulatory bodies, medical professional organizations, and medical licensing boards. TMS is particularly attractive to probe various aspects of brain function, as it has minimal side effects. Research studies should be approved by local ethics committees.

J Magn Reson Imaging 13:534–546, 2001 Li X, Nahas Z, Lomarev M, et al: Prefrontal cortex transcranial magnetic stimulation does not change local diffusion: a magnetic resonance imaging study in patients with depression. Cogn Behav Neurol 16:128–135, 2003 Liebetanz D, Fauser S, Michaelis T, et al: Safety aspects of chronic low-frequency transcranial magnetic stimulation based on localized proton magnetic resonance spectroscopy and histology of the rat brain. J Psychiatr Res 37:277–286, 2003 Lisanby SH, Sackeim HA: Therapeutic brain interventions and the nature of emotion, in The Neuropsychology of Emotion.

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