Download Primary Sclerosing Cholangitis: Current Understanding, by Lisa M. Forman PDF
By Lisa M. Forman
This textual content presents a state-of-the artwork evaluation of basic sclerosing cholangitis (PSC). the amount makes a speciality of new info approximately threat elements for PSC, its average historical past of the ailment, and the epidemiology and genetics of PSC, whereas supplying a finished assessment on present and destiny cures for PSC, administration of cholangiocarcinoma, and different hepatobiliary malignancies. It additionally touches upon up to date surgical and endoscopic administration, together with liver transplantation- either deceased donor and residing comparable liver transplantation. Written by way of specialists within the box, Primary Sclerosing Cholangitis: present realizing, administration, and destiny Developments is a important source for clinicians, surgeons and researchers with an curiosity in biliary liver sickness, inflammatory bowel illness, and liver transplantation.
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Additional info for Primary Sclerosing Cholangitis: Current Understanding, Management, and Future Developments
Example text
This risk does not appear to be affected by liver disease severity [92] or worsen after liver transplantation [94]. 047) [95]. Neoplasia of the pouch or anal transition zone (ATZ) following IPAA has been described [96, 97] and occurs more often in patients undergoing colectomy for dysplasia/CRC [96]. Some studies suggest that PSC-IBD patients are at increased risk for pouch or ATZ neoplasia [98, 99]. The overall rate of pouch/ATZ neoplasia remains low, however, and there is no consensus on the need, or optimal protocol, for surveillance for pouch/ ATZ neoplasia following IPAA [98, 100].
J Hepatol. 1997;27(3): 512–6. Heimbach JK, Sanchez W, Rosen CB, Gores GJ. Transperitoneal fine needle aspiration biopsy of hilar cholangiocarcinoma is associated with disease dissemination. HPB Off J Int Hepato Pancreato Biliary Assoc. 2011;13(5):356– 60. 00298. Hong JC, Jones CM, Duffy JP, et al. Comparative analysis of resection and liver transplantation for intrahepatic and hilar cholangiocarcinoma: a 24-year experience in a single center. Arch Surg. 2011;146(6):683–9. Kozarek RA. Single-operator cholangioscopes in the diagnosis of cholangiocarcinoma: seeing is believing.
Gastroenterology. 1991;100(6):1710–7. Epub 1991/06/01. 11. Kornfeld D, Ekbom A, Ihre T. Is there an excess risk for colorectal cancer in patients with ulcerative colitis and concomitant primary sclerosing cholangitis? A population based study. Gut. 1997;41(4):522– 5. Epub 1997/12/10. 12. Loftus Jr EV, Harewood GC, Loftus CG, Tremaine WJ, Harmsen WS, Zinsmeister AR, et al. PSC-IBD: a unique form of inflammatory bowel disease associated with primary sclerosing cholangitis. Gut. 2005;54(1):91–6. Epub 2004/12/14.