Download The Diversity of Gastric Carcinoma: Pathogenesis, Diagnosis by M. Kaminishi, K. Takubo, K. Mafune PDF
By M. Kaminishi, K. Takubo, K. Mafune
Japan has lengthy been a pacesetter of analysis into the carcinogenesis, pathology, analysis, and therapy of gastric carcinoma, that's nonetheless the second one prime reason behind melanoma loss of life world wide. unique specialists within the box collaborated in developing this groundbreaking paintings, offering a entire view of gastric melanoma. This ebook encourages additional improvement of gastric melanoma learn and its scientific software. themes comprise all features of gastric carcinoma, comparable to the historical past of medical and experimental gastric melanoma study; up to date problems with molecular and pathological study on gastric carcinogenesis; multidisciplinary equipment in prognosis, remedy, and chemotherapy; and views in minimally invasive surgical procedure. colour figures of histological specimens and different medical positive aspects help readers in with no trouble realizing the textual descriptions, making this quantity a priceless resource for clinicians and researchers alike.
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Hattori T, Helpap B, Gedigk P (1982) The morphology and cell kinetics of pseudopyloric glands. Virchows Arch B Cell Pathol Mol Pathol 39:31–40 64. Karam SM, Leblond CP (1993) Dynamics of epithelial cells in the corpus of the mouse stomach. I. Identification of proliferative cell types and pinpointing of the stem cell. Anat Rec 236:259–279 65. Ponder BA, Schmidt GH, Wilkinson MM, et al (1985) Derivation of mouse intestinal crypts from single progenitor cells. Nature (Lond) 313:689–691 66. Tatematsu M, Fukami H, Yamamoto M, et al (1994) Clonal analysis of glandular stomach carcinogenesis in C3H/HeN´BALB/c chimeric mice treated with N-methyl-Nnitrosourea.
320 a b c d e f Fig. 4. Intestinal phenotypic expression in both differentiated (a–c) and undifferentiated (d–f) type gastric carcinomas. a, d H&E stain; b, e MUC2 is evident in the cytoplasm of cancer cells; c, f villin is apparent at the luminal surfaces of cancer cells. Inset, higher magnification of villinpositive tumor cells in a signet ring cell carcinoma a–c ¥400; d–f ¥320; red squares indicate a element ¥640 Historical Review of Research and Treatment of Gastric Cancer in Japan: Clinical Aspect Toshifusa Nakajima Introduction Gastric cancer has been decreasing in incidence in Western countries, but it still remains a leading cause of death in the world.
It has provided the common basis of documentation to facilitate the Nationwide Registry of Gastric Cancer since 1969 [32]. Lymph Node Dissection As stated previously, metastasis to the lymph nodes is the most frequent type of cancer spread, which could only be controlled by surgeons with meticulous lymphadenectomy. Kajitani [26] stressed the importance of wide dissection of regional lymph nodes to eradicate lymphatic spread in 1944, and Jinnai [27] also advocated a systematic radical gastrectomy in 1961.