Download Tools and Applications of Biochemical Engineering Science by K. Schugerl, A. -P Zeng PDF
By K. Schugerl, A. -P Zeng
This distinct quantity "Tools and purposes of Biochemical Engineering technology" is devoted to Professor Wolf-Dieter Deckwer at the social gathering of his sixtieth bir- day. It was once a superb excitement for me to behave including Professor Karl Schtigerl as quantity editor and to give the following a suite of eleven remarkable evaluation articles written as a rule via former scholars, affiliates, colleagues and associates of Wolf- Dieter Deckwer. The identify of this specific quantity good displays the examine pursuits and sci- tific pursuit of Wolf-Dieter Deckwer in the course of his greater than two decades’ paintings within the zone of biochemical engineering, fairly over the last 15 years whilst he was once the top of the Biochemical Engineering department of GBF (German Nat- nal examine heart for Biotechnology). He has decisively driven the devel- ment not just of "software instruments" starting from analytical capability and mathe- tical versions for tracking and figuring out mobile techniques to gene expression platforms for designing microorganisms, but additionally of "hardware instruments" similar to desktop keep watch over platforms, bioreaction and separation units for eff- tively generating quite a few bioproducts on semi-production scale. New advancements in a few of these vital instruments in biochemical engineering are reviewed in articles integrated during this quantity. Wolf-Dieter Deckwer was once one of the major biochemical engineers who well timed mentioned the need of utilizing those instruments in an built-in demeanour for bioprocess improvement. through developing "Integrated Bioprocess improvement" as one of many GBF major - seek issues as early as 1990 he additionally actively promoted this concept.
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59 Tissue Cultures . . . . . . . . . . . . . . . 60 In vivo Studies in Animals and Humans . . . . . . . . 61 6 Conclusions and Future Perspectives . . . . . . . . . 61 References . . . . . . . . . . . . . . . . . . 62 List of Symbols and Abbreviations c F Im1/m2 s S x AMM CI CID EI ESI FAB FMDV GC HPLC ICP IDV IR MS IMM MALDI MCP MDV ME MI MS MS NMR PPP SEM SIM molar cumomer fraction flux parameter, flux partitioning ratio intensity ratio of mass isotopomer pools m1 and m2 sum of squares of relative deviations flux sensitivity molar fraction atom mapping matrix chemical ionization collision induced decay electron impact electrospray ionization fast atom bombardment fragment mass isotopomer distribution vector gas chromatography high pressure liquid chromatography inductively coupled plasma isotopomer distribution vector isotope ratio mass spectrometry isotopomer mapping matrix matrix-assisted laser desorption ionization microchannel plate mass distribution vector molar enrichment membrane inlet mass spectrometry mass spectrometry nuclear magnetic resonance pentose phosphate pathway secondary electron multiplier selective ion monitoring, single ion monitoring Metabolic Flux Analysis Using Mass Spectrometry TCA TOF TSQ 41 tricarboxylic acid time-of-flight triple stage quadrupole 1 Introduction Metabolic engineering aims at a targeted improvement of cellular properties.
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