Download Towards Offline PET Monitoring at a Cyclotron-Based Proton by Matthias Würl PDF

By Matthias Würl

Matthias Würl offers crucial steps to enforce offline puppy tracking of proton dose supply at a medical facility, particularly the constructing of a correct Monte Carlo version of the scientific beamline and the experimental validation of positron emitter construction cross-sections. within the first half, the sector measurement dependence of the dose output is defined for scanned proton beams. either the Monte Carlo and an analytical computational beam version have been capable of appropriately expect objective dose, whereas the latter has a tendency to overestimate dose in common tissue. within the moment half, the writer offers puppy measurements of alternative phantom fabrics, that have been activated via the proton beam. the implications point out that for an irradiation with a excessive variety of protons for the sake of excellent data, lifeless time losses of the puppy scanner may perhaps develop into vital and result in a sarcasm of positron-emitter creation yields.

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Extra info for Towards Offline PET Monitoring at a Cyclotron-Based Proton Therapy Facility: Experiments and Monte Carlo Simulations

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3 presents a comparison of TPS calculation, MC simulation and measured dose for different sizes of homogeneous dose spheres. 4. 1 Lateral profile of a single pencil beam Although not perfectly describing the lateral profile of a scanned proton beam, treatment planning systems usually use Gaussian distributions to describe the lateral profile since it is computationally efficient and therefore suitable for routine treatment planning. Pedroni et al. [2005] proposed to parametrize the beam width by a so-called double Gaussian.

Tency. Therefore, the density of water at room-temperature is used as density of gelatine. 3 mm. The ionization potentials of the three materials can not be measured directly.

This can also be seen for pencil beams at different energies, though not shown here. However, it has to be stressed that the measurement of the BP chamber is more uncertain in the peak region. This is due to the energy dependence of the stopping power ratio and possible saturation effects of the chamber. 3 Conclusion Overall good agreement between simulation and measured doses could be achieved for all sphere sizes. The slightly larger differences in the plateau are consistent with independent measurements and simulations of single pencil beams in water.

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