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By Henry Parkman MD
This factor of Gastroenterology Clinics of North the US is on Gastrointestinal Motility problems. GI motility problems are universal purposes for sufferers to work out gastroenterologists. wisdom of the pathophysiology, overview and therapy of those issues is critical to properly deal with sufferers with gastrointestinal motility problems in medical perform. The chapters of this factor will speak about key points of gastrointestinal motility issues targeting how they relate to practising gastroenterologists and different well-being care companies. present wisdom within the quarter in addition to evolving thoughts from scientific investigations and translational study from easy sciences could be mentioned. The speedy explosion of recent expertise utilized in the overview of sufferers can be lined.
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Additional resources for Gastrointestinal Motility Disorders, An Issue of Gastroenterology Clinics (The Clinics: Internal Medicine)
Sample text
Parkman HP, Hasler WL, Barnett JL, et al. Electrogastrography: a document prepared by the gastric section of the American Motility Society Clinical GI Motility Testing Task Force. Neurogastroent Motil 2003;75:89–102. Lin HC, Prather C, Fisher RS, et al. AMS Task Force Committee on Gastrointestinal Transit. Measurement of gastrointestinal transit. Dig Dis Sci 2005;50(6): 989–1004. Colon/rectum Rao SS, Azpiroz F, Diamant N, et al. Minimum standards of anorectal manometry. Neurogastroent Motil 2002;14(5):553–9.
These observations are intriguing because it seems that impedance may help define treatment strategies for various patient groups: spasm patients with poor bolus transit and normal or low contractile amplitudes are not likely to respond to therapy focused on relaxing the smooth muscle esophagus, whereas chest pain patients with extremely high contractile amplitudes may be a subpopulation with a good response to nitrates and calcium channel blockers. The stage is set for defining patient subtypes and performing prospective interventional outcome trials.
Adv Anat Embryol Cell Biol 1982;71:1–130. [37] Ward SM, Burns AJ, Torihashi S, et al. Mutation of the proto-oncogene c-kit blocks development of interstitial cells and electrical rhythmicity in murine intestine. J Physiol 1994;480 (Pt 1):91–7. [38] Huizinga JD, Thuneberg L, Kluppel M, et al. W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature 1995;373(6512):347–9. [39] Hara Y, Kubota M, Szurszewski JH. Electrophysiology of smooth muscle of the small intestine of some mammals.