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By Edited by: Hirokazu Takahashi
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Set of tests which should be made directly before blind liver biopsy. 7. The choice of type of liver biopsy Focal changes discovered in ultrasound examination or computed tomography are indications for an image-controlled biopsy. In patient with chronic hepatitis in whom a solid focal change is diagnosed two USG-guided core biopsies should be made. The first specimen should be obtain from the solid lesion. The other should be obtained from other part of liver (with the avoidance of lesion volume).
1994). This finding, however, remains controversial and it does not help distinguish autoimmune liver disease from viral hepatitis. 1 Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) The liver histology of patients with PBC has been extensively analyzed. A characteristic early stage histologic feature in these patients is nonsuppurative destructive cholangitis. Although the biliary epithelium is thought to be the target for host immune responses, the mechanism underlying epithelial destruction is unclear.
References [1] Scheuer PJ & Lefkowitch JH. Liver Biopsy Interpretation. 7th Edition. Edinburgh: Elsevier [2] Sherlock S & Dooley J. (2002). Diseases of the Liver and Biliary System. 11th ed. Oxford: Blackwell Science 32 Liver Biopsy [3] Bruno MA, Rodríguez Fuchs C, Gallo J, González Boix J. (1990) Percutaneous hepatic biopsy puncture in patients with hemostasis disorders. A new technique. 20, No1, pp. 25-30 [4] M Horejsová & F Koukolík (1989). Thin-needle aspiration biopsy under ultrasonic control.