Download Liver Transplantation: Clinical Assessment and Management by James Neuberger, James Ferguson, Philip N. Newsome PDF
By James Neuberger, James Ferguson, Philip N. Newsome
Liver Transplantation: Clinical review and Management is the fitting instrument for all gastroenterologists, hepatologists and transplant surgeons coping with sufferers with liver ailment watching for and present process transplantation.
Led by means of James Neuberger, international specialists in hepatology and transplantation offer a chronological, step-by-step method of most sensible medical administration and sufferer care.
Evidence-based all through and almost about the very most recent perform guidance from significant societies similar to EASL and AASLD, the booklet covers:
- When to refer a sufferer for liver transplantation
- Selection, overview and administration at the list
- Transplantation for acute liver failure
- Donation and allocation
- Care of the liver transplant recipient
80 excessive definition video clips of transplant surgical procedure let you watch the specialists in motion and supply a very good visible and teaching element. additionally, key issues, strength pitfalls, administration algorithms, and invaluable weblinks all aid verify speedy reference browsing.
If you are dealing with sufferers requiring a liver transplant, this multimedia source will prevent effort and time via placing crucial details inside of effortless succeed in
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Additional info for Liver Transplantation: Clinical Assessment and Management
Sample text
In contrast, severe acute alcoholic hepatitis (SAAH), which carries a significant mortality, has not been an indication for liver transplantation in many countries. Despite that, retrospective series and a recent prospective study from France of transplantation in highly selected cases with SAAH have reported encouraging results. Rates of resumption of alcohol use were similar to those reported in other series of patients following transplantation for alcoholic liver disease. General Considerations 15 Summary • All patients who are potential transplant candidates and have consumed alcohol to excess must be assessed by multidisciplinary teams expert in the management of addictive behaviours.
Broadly speaking, these fall under three headings: (1) previous or existing psychiatric illness; (2) substance abuse; (3) social support networks. In the setting of chronic liver disease, significant psychiatric illness should be under good control before listing for LT. Concerns about compliance with medications or clinic attendance should be viewed as a relative contraindication to listing. Patients presenting with acute liver failure caused by an attempted suicide should be evaluated carefully.
Although the duration of abstinence prior to transplantation has some predictive value for sobriety, there is little evidence to support a rigid 6-month rule. Not all studies have demonstrated that the duration of abstinence is inversely a strong predictor of recidivism, and other factors including psychiatric comorbidities, social support networks, poly-substance misuse and age at onset of abuse are also critical. Some countries, for example the UK and France, have moved away from a 6-month rule to a comprehensive psychosocial assessment.